2-{[(4-methylpyridin-2-yl)amino]methyl}phenol
2-{[(4-methylpyridin-2-yl)amino]methyl}phenol
CAS: 104768-35-6
Molecular Formula: C13H14N2O
2-{[(4-methylpyridin-2-yl)amino]methyl}phenol - Names and Identifiers
| Name | 2-{[(4-methylpyridin-2-yl)amino]methyl}phenol |
| Synonyms | CHEMBRDG-BB 9070478 2-([(4-METHYL-2-PYRIDINYL)AMINO]METHYL)PHENOL 2-{[(4-methylpyridin-2-yl)amino]methyl}phenol phenol, 2-[[(4-methyl-2-pyridinyl)amino]methyl]- |
| CAS | 104768-35-6 |
| InChI | InChI=1/C13H14N2O/c1-10-6-7-14-13(8-10)15-9-11-4-2-3-5-12(11)16/h2-8,16H,9H2,1H3,(H,14,15) |
2-{[(4-methylpyridin-2-yl)amino]methyl}phenol - Physico-chemical Properties
| Molecular Formula | C13H14N2O |
| Molar Mass | 214.26 |
| Density | 1.206g/cm3 |
| Boling Point | 394°C at 760 mmHg |
| Flash Point | 192.1°C |
| Vapor Presure | 8.98E-07mmHg at 25°C |
| Storage Condition | Room Temprature |
| Refractive Index | 1.655 |
2-{[(4-methylpyridin-2-yl)amino]methyl}phenol - Introduction
2-([(4-methyl-2-pyridyl) amino] methyl) phenol, also known as Benzydamine, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless crystal or crystalline powder.
-Solubility: Soluble in water and organic solvents.
-Melting point: about 156-160°C.
- pH: alkaline in aqueous solution.
Use:
-CLINICAL APPLICATIONS: 2-([(4-METHYL-2-PYRIDYL) AMINO] METHYL) PHENOL is commonly used in the mouth and throat as a local anesthetic and anti-inflammatory drug to relieve pain and reduce inflammation.
-Cosmetics: In some oral and throat care products, this compound is also used as a preservative.
Preparation Method:
The preparation of 2-([(4-methyl-2-pyridyl) amino] methyl) phenol is usually carried out by the following steps:
1. First, 4-methyl -2-fluoropyridine and formaldehyde are reacted to produce α-[4-methyl -2-pyridyl] methyl alcohol.
2. Then, α-[4-methyl -2-pyridyl] methyl alcohol is reacted with sulfonyl chloride to generate the corresponding α-[4-methyl -2-pyridyl] methanesulfonyl chloride compound.
3. Finally, the α-[4-methyl-2-pyridyl] methanesulfonyl chloride compound is reacted with phenol to produce 2-([(4-methyl-2-pyridyl) amino] methyl) phenol.
Safety Information:
- 2-([(4-Methyl-2-pyridyl) amino] methyl) phenol is generally relatively safe under normal conditions of use, but the following precautions still need to be followed:
-Non-oral: only for external use, avoid accidental ingestion.
-Allergic reaction: Some people may be allergic to this compound, and allergy testing should be performed before use.
-Use in children: Use in children under the supervision of a health care professional.
Please note that the above information is for reference only. Please read the product manual carefully before use, and consult a professional doctor or pharmacist for advice if necessary.
Nature:
-Appearance: Colorless crystal or crystalline powder.
-Solubility: Soluble in water and organic solvents.
-Melting point: about 156-160°C.
- pH: alkaline in aqueous solution.
Use:
-CLINICAL APPLICATIONS: 2-([(4-METHYL-2-PYRIDYL) AMINO] METHYL) PHENOL is commonly used in the mouth and throat as a local anesthetic and anti-inflammatory drug to relieve pain and reduce inflammation.
-Cosmetics: In some oral and throat care products, this compound is also used as a preservative.
Preparation Method:
The preparation of 2-([(4-methyl-2-pyridyl) amino] methyl) phenol is usually carried out by the following steps:
1. First, 4-methyl -2-fluoropyridine and formaldehyde are reacted to produce α-[4-methyl -2-pyridyl] methyl alcohol.
2. Then, α-[4-methyl -2-pyridyl] methyl alcohol is reacted with sulfonyl chloride to generate the corresponding α-[4-methyl -2-pyridyl] methanesulfonyl chloride compound.
3. Finally, the α-[4-methyl-2-pyridyl] methanesulfonyl chloride compound is reacted with phenol to produce 2-([(4-methyl-2-pyridyl) amino] methyl) phenol.
Safety Information:
- 2-([(4-Methyl-2-pyridyl) amino] methyl) phenol is generally relatively safe under normal conditions of use, but the following precautions still need to be followed:
-Non-oral: only for external use, avoid accidental ingestion.
-Allergic reaction: Some people may be allergic to this compound, and allergy testing should be performed before use.
-Use in children: Use in children under the supervision of a health care professional.
Please note that the above information is for reference only. Please read the product manual carefully before use, and consult a professional doctor or pharmacist for advice if necessary.
Last Update：2024-04-09 21:01:54
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CAS: 104768-35-6
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